🇵🇹Portuguese Source WordCode: PT

recetor aberto

Pronunciation / Transliteration: ʁesepˈtoʁ aˈbɛʁtu

🇬🇧 Direct English Meaning:
Open receptor/ˈoʊ.pən rɪˈsɛp.tər/
nounCEFR C1 (Advanced)Top #42500 frequency
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🇵🇹 Example Sentence in Portuguese:

"O canal iónico encontra-se no estado de recetor aberto."

Comprehensive Definitions & Senses

2 senses
As noun
  1. 1

    A biological receptor or ion channel conformation that is currently accessible or unbound, allowing ions or signaling molecules to pass or bind freely.

    "The local anesthetic blocks the sodium channel primarily when it is in the open receptor conformation."
  2. 2

    In theoretical models of signal transduction, a receptor site that lacks steric hindrance and is fully receptive to agonist binding.

    "Investigators measured the affinity of the radioligand for the open receptor state."

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Linguistic Origin & Historical Etymology

Derived from the English adjective 'open' (from Old English 'open', of Germanic origin) combined with 'receptor' (from Latin 'receptor', one who receives, from 'recipere'). The physiological and pharmacological usage developed in the 20th century to describe channel conformations or binding sites readily accessible to ligands.

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