The square root of 4,225 is 65.
Explanation: To find the square root of a number, you are looking for a value that, when multiplied by itself, gives you that number. In this case, if you multiply 65 by 65 (or 65²), you get 4,225. You can also confirm this using a calculator or by breaking it down into factors, showing that 65 is indeed the correct square root.