The largest organ system in the human body is the skin system, commonly referred to as the integumentary system. This system includes the skin itself, along with its associated structures such as hair, nails, and glands.
The integumentary system serves several essential functions. It acts as a protective barrier against environmental hazards such as pathogens and harmful UV rays. Additionally, it helps regulate body temperature, prevents water loss, and plays a critical role in sensory perception through nerve endings that detect touch, pain, and temperature. The skin is not only the largest organ by surface area but also one of the most vital in maintaining overall health and homeostasis in the body.