Answer: False.
The adrenal glands, while significant as endocrine glands, are not the largest. The largest purely endocrine gland in the human body is the thyroid gland. The adrenal glands are located on top of each kidney and are responsible for producing hormones like adrenaline and cortisol, which help regulate metabolism, immune response, and stress. However, the thyroid gland, located in the neck, plays a crucial role in metabolism regulation by producing hormones such as thyroxine and triiodothyronine. Therefore, the statement is incorrect.