World Languages Lexicon
10 Language-to-English DictionariesRefractoriness
/rɪˈfræktərɪnəs/Comprehensive Definitions & Senses
2 senses- 1
The quality or state of being stubborn, obstinate, or unyielding to control, guidance, or treatment.
"The patient's refractoriness to standard chemotherapy forced the oncology team to consider an experimental trial." - 2
In physiology, the period of recovery during which a nerve or muscle fiber is unresponsive to a second stimulus.
"Cardiac refractoriness prevents the heart muscle from going into a continuous, fatal tetanus contraction."
Thesaurus & Semantic Spectrum
Linguistic Origin & Historical Etymology
Derived from the Latin adjective 'refractarius' (stubborn, obstinate), from 'refractare' (to break back or resist), combining the prefix 're-' with 'fractus' (broken). Entering the English language in the late 16th century via French, the term originally denoted stubbornness or unruliness before expanding into technical domains such as metallurgy, medicine, and electronics to describe resistance to heat, treatment, or stimulation.
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10 Global Lexicons: How "Refractoriness" is said worldwide
Click any language below to open its dedicated Language to English dictionary page with native script & transliteration
caractère réfractaire
Transliteration: kaʁaktɛʁ ʁɛfʁaktɛʁ
"La réfractarité de la maladie a surpris les médecins."
Refraktarität
Transliteration: ʁefʁaktaʁiˈtɛːt
"Die Refraktarität des Gewebes schützt das Herz vor Übererregung."
refrattarietà
Transliteration: refrattarietà
"La refrattarietà del paziente ai farmaci ha complicato le cure."
refractariedad
Transliteration: refraktariedad
"Se investiga la refractariedad al tratamiento en estos tumores."
refratariedade
Transliteration: hɛfɾataɾiˈdadʒi
"A refratariedade do tumor exigiu uma nova abordagem terapêutica."
अड़ियलपन
Transliteration: adiyalpan
"रोग की अड़ियलपन ने डॉक्टरों को चिंतित कर दिया।"
难治性
Transliteration: nán zhì xìng
"这种疾病表现出对常规药物的强烈难治性。"
난치성
Transliteration: nanchiseong
"약물에 대한 난치성 때문에 치료가 지연되었습니다."
難治性
Transliteration: nanjisei
"その病気の難治性に医療チームは苦慮した。"
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