Definition, Meaning & Synonyms

metabotropic

Adjective
/ˌmɛtəˈbɒtrəpɪk/
Definition
Referring to a type of receptor that, upon binding a neurotransmitter, leads to indirect changes in cellular activity through a cascade of biochemical events.
Examples
  • The metabotropic glutamate receptors play key roles in modulating synaptic transmission.
  • Researchers are studying how metabotropic pathways affect mood and behavior.
  • Activation of metabotropic receptors can lead to long-lasting changes in neuronal activity.
Meaning
Metabotropic receptors are involved in signal transduction that affect the function of neurons and other cells via intermediary molecules.
Synonyms
  • Biochemical receptor
  • Signaling receptor
  • G-protein coupled receptor (GPCR)