The expeditions of Hernán Cortés and Francisco Pizarro primarily resulted in the destruction of the Aztec and Inca empires. Cortés led the expedition that led to the fall of the Aztec Empire in present-day Mexico, while Pizarro conquered the Inca Empire in Peru. Both conquests had profound implications for the indigenous populations and altered the course of history in the Americas.
The other options such as the capture of Brazil by Portugal, the colonization of North America by Portugal, and the exploration of the Philippines and East Indies are not directly linked to the actions of Cortés and Pizarro. Instead, Brazil was primarily colonized by the Portuguese and other regions, such as North America, saw explorations by various European powers, including the English and French. Therefore, it is important to understand the specific contributions and impacts of these two conquistadors in the context of Spanish imperial expansion in the New World.