What type of bonding between the A-T and G-C base pairs helps hold the two DNA strands in duplex together?

The bonding between the adenine-thymine (A-T) and guanine-cytosine (G-C) base pairs in DNA is primarily due to hydrogen bonds.

A-T base pairs are held together by two hydrogen bonds, while G-C pairs are connected by three hydrogen bonds. This difference in the number of hydrogen bonds contributes to the overall stability of the DNA double helix structure.

The hydrogen bonds between these complementary base pairs are crucial for the integrity of the DNA molecule. They allow the strands to come together in a specific and complementary manner, ensuring that genetic information is accurately preserved and transmitted. This pairing rule is known as Chargaff’s rules, which states that in any DNA molecule, the amount of adenine equals thymine and the amount of guanine equals cytosine.

Overall, it’s this specific hydrogen bonding that not only stabilizes the double-stranded structure of DNA but also allows for the intricate processes of DNA replication and transcription to occur efficiently.

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