The medical term that aligns with the definition ‘pertaining to through the skin’ is transdermal.
Explanation: The prefix ‘trans-‘ means ‘through’ or ‘across,’ and ‘dermal’ relates to the skin. Transdermal is often used in reference to medications or therapies that are administered through the skin for systemic effects, such as transdermal patches for pain relief or hormone replacement therapy. This method allows drugs to bypass the digestive system and enter the bloodstream directly, providing a more efficient delivery system for certain treatments.