The genotype of a normal human male is typically represented as 46,XY. This means that a normal male has a total of 46 chromosomes, which includes 22 pairs of autosomes and one pair of sex chromosomes.
The ‘XY’ designation indicates that the male has one X chromosome and one Y chromosome. The presence of the Y chromosome is what defines human males genetically, as it carries the SRY gene that triggers male sex development.
In contrast to females, who have two X chromosomes (genotype 46,XX), males inherit one X chromosome from their mother and one Y chromosome from their father. This unique combination of sex chromosomes leads to the development of male characteristics and determines various aspects of male physiology.