Autocrine signaling refers to a type of cell signaling where a cell produces a signal that binds to receptors on its own surface, affecting its own behavior. Several hormones and factors act through autocrine signaling.
One notable example is interleukin-1 (IL-1), a cytokine produced by various cells, particularly immune cells. IL-1 can bind to receptors on the same cells that secrete it, promoting inflammatory responses.
Another example is growth factors, like epidermal growth factor (EGF). EGF can stimulate the same cells that release it to promote cell growth and proliferation.
Additionally, prostaglandins also function in an autocrine manner. They play roles in processes like inflammation and are produced by many cells, acting on receptors of the same cells that released them.
Overall, these hormones and factors illustrate the importance of autocrine signaling in regulating various cellular functions, particularly in immune responses and cell growth.