The siege of Constantinople in 1453 resulted in a considerable loss of life, but precise numbers vary. Historical estimates suggest that the population of the city before the siege was around 50,000 to 100,000 people. During the siege, which lasted from April 6 to May 29, many inhabitants died due to combat, bombings, and diseases. It’s estimated that between 4,000 and 10,000 defenders died during the fighting.
After the city fell, there was an increase in death toll due to the massacre and enslavement of many residents. Some accounts suggest that tens of thousands may have perished in the aftermath. Overall, while exact figures are hard to pinpoint, it’s clear that the siege was catastrophic for the city’s population.