Prokaryotes primarily contain circular double-stranded DNA that is located in a region called the nucleoid. However, some prokaryotic viruses, known as bacteriophages, can indeed have single-stranded DNA. In addition, certain prokaryotes can have plasmids, which are small, circular DNA molecules that can exist independently of chromosomal DNA and can be either double-stranded or single-stranded. So, while the main genetic material in prokaryotes is typically double-stranded, the presence of single-stranded DNA can occur in specific contexts.
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