The short answer is no, the Appalachian Mountains do not run directly through South Carolina. While the Appalachian Mountains span a vast area through several states, including parts of Virginia, West Virginia, North Carolina, and Tennessee, their presence in South Carolina is more indirect.
In South Carolina, you will find the foothills of the Appalachian Mountains, particularly in the northwest region of the state. The Blue Ridge Mountains, which are a segment of the larger Appalachian range, extend into North Carolina and are very close to the border with South Carolina. The highest peak in South Carolina, Sassafras Mountain, is located within this region and is part of the Blue Ridge range.
So, while the Appalachian Mountains themselves do not officially cover South Carolina, the state does encompass areas that are influenced by these mountains, specifically in the northwest corner. This area features beautiful landscapes, opportunities for hiking, and is home to some of the state’s most stunning natural scenery.