Definition, Meaning & Synonyms
transpeptidation
noun
/ˌtrænspɛp.tɪˈdeɪ.ʃən/
Definition
Transpeptidation is a biochemical process in which one peptide bond is formed by transferring a peptide group from one amino acid to another, typically during the synthesis of proteins.
Examples
- During bacterial cell wall synthesis, the transpeptidation reaction is a critical step for forming strong and stable structures.
- The action of antibiotics often involves inhibiting transpeptidation, preventing bacteria from properly forming their cell walls.
- Transpeptidation can also occur in the formation of enzymes and other proteins within the cell.
Meaning
This process is essential in the formation of peptide linkages during protein synthesis, which is crucial for cell growth and repair.
Synonyms
- Peptide bond formation
- Peptide transfer
- Amino acid linkage
