Definition, Meaning & Synonyms

tachyphylaxis

noun
ˌtak-ē-fə-ˈlak-səs
Definition
A rapidly diminishing response to successive doses of a drug, often leading to the need for increasing amounts to achieve the same effect.
Examples
  • Doctors observed tachyphylaxis in patients receiving repeated doses of certain pain medications.
  • Due to tachyphylaxis, the patient required higher doses of the drug to achieve the desired effect.
Meaning
Tachyphylaxis refers to a situation where the body becomes less responsive to a substance after repeated doses over a short period.
Synonyms
  • Desensitization
  • Acute tolerance