Definition, Meaning & Synonyms

metaplasia

noun

/ˌmɛtəˈpleɪziə/

Definition

Metaplasia is the process where one type of mature, differentiated cell transforms into another type of mature, differentiated cell.

Examples

In the study of pathology, scientists observed metaplasia in the respiratory tract due to prolonged exposure to cigarette smoke.
Metaplasia can be seen in Barrett’s esophagus, where squamous cells transform into columnar cells in response to acid reflux.

Meaning

This biological transformation usually occurs in response to chronic irritation or inflammation, allowing tissues to adapt to changes in their environment.