Definition, Meaning & Synonyms
ionotropic receptor
Noun
/ˌaɪə.nəˈtrɒp.ɪk rɪˈsiː.p.tər/

Definition
A type of receptor that allows the passage of ions across a cell membrane in response to the binding of a neurotransmitter.

Examples
- The ionotropic receptors respond quickly to neurotransmitters, making them crucial for rapid signaling in the nervous system.
- Glutamate acts on ionotropic receptors, leading to excitatory postsynaptic potentials.
- Muscle contractions are influenced by ionotropic receptors at the neuromuscular junction.

Meaning
Ionotropic receptors are integral membrane proteins that mediate fast synaptic transmission by changing their conformation when they bind neurotransmitters, leading to the opening or closing of ion channels.

Synonyms
- Ligand-gated ion channels
- Ion channel receptors