Definition, Meaning & Synonyms

centromere

noun
/ˈsɛntrəˌmɪr/
Definition
The centromere is a region of a chromosome that links sister chromatids (the two identical copies of a chromosome) and is essential for proper chromosome segregation during cell division.
Examples
  • The centromere plays a crucial role in cell division.
  • During mitosis, the spindle fibers attach to the centromere of each chromosome.
  • Errors in centromere function can lead to genetic disorders.
Meaning
It is the part of a chromosome that helps ensure that DNA is accurately divided into daughter cells during mitosis and meiosis.
Synonyms
  • chromosomal centromere
  • kinetochore (when referring to the protein complex at the centromere)