Definition, Meaning & Synonyms

anaplasia

noun

ˌænəˈpleɪziə

Definition

Anaplasia is a term used in pathology to describe the loss of differentiation and a return to a more primitive or unspecialized state of cells.

Examples

In cancer research, anaplasia is a key indicator of tumor aggressiveness.
The biopsy revealed signs of anaplasia, suggesting a more severe form of the disease.

Meaning

It refers to the process whereby mature cells lose their specific characteristics and become more like immature cells, often indicating a malignant transformation.