Definition, Meaning & Synonyms
missense
noun
ˈmɪs.sɛns
Definition
A missense mutation is a type of genetic mutation where a single nucleotide change results in the substitution of one amino acid for another in the protein produced by the gene.
Examples
- The missense mutation in the gene led to a malfunctioning enzyme.
- Scientists studied how missense variations can influence the development of certain diseases.
Meaning
It refers to a situation in genetics where the incorrect building block (amino acid) is added to a protein, which can affect the protein’s function.
Synonyms
- nonsynonymous mutation
- amino acid substitution
