No, Salmon P. Chase and Samuel Chase were not directly related, though they shared a common surname and some notable historical connections.
Salmon P. Chase (1808-1873) was a prominent American politician and abolitionist, best known for serving as the Secretary of the Treasury under President Abraham Lincoln and later as Chief Justice of the United States. He played a significant role in the financial policies of the Union during the Civil War.
On the other hand, Samuel Chase (1741-1811) was an associate justice of the Supreme Court who was appointed by President George Washington. He was a signatory of the Declaration of Independence and is known for his strong support of independence from Britain.
While both men were influential in American history, their familial ties are not documented, and their contributions were made in different centuries and contexts. The similarity in their last names might lead to some confusion, but they were not related by blood or marriage.