Definition, Meaning & Synonyms

paracrine

Adjective
/ˈpærəˌkraɪn/
Definition
Relating to the method of cell signaling in which a cell produces a signal to induce changes in nearby cells.
Examples
  • The paracrine signaling between immune cells helps regulate the immune response.
  • In the study of development, paracrine factors can influence the growth of surrounding tissues.
  • Growth factors often act in a paracrine manner, affecting nearby cells to encourage proliferation.
Meaning
Paracrine signaling involves the release of signaling molecules that affect neighboring cells within a short distance, rather than traveling through the bloodstream.
Synonyms
  • Local signaling
  • Cell-to-cell signaling
  • Juxtacrine signaling